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There are insufficient data in pediatric patients with type 2 diabetes treated with Wegovy for obesity to determine if there is an increased risk of hypoglycemia with Wegovy treatment similar to that reported in adults Geriatric: In the cardiovascular outcomes trial, patients aged 75 years and older reported more hip and pelvis fractures on Wegovy than placebo

The insulin sensitivity improvements deserve specific mention

[15] Ligands [edit] GLP1R binds glucagon-like peptide-1 (GLP1) and glucagon as its natural endogenous agonists

Healthcare Systems and Providers: As referenced above, health systems will need to understand how a reduction in certain diseases and a healthier population will impact the demand for different services, and how they need to adapt their service configuration to meet evolving population needs